Will Greenleaf

My lab is interested in leveraging the power of high-throughput sequencing methods to 1) understand rare genomic and epi-genomic heterogeneity at the level of cellular subpopulations and even single cells 2) investigate chromatin structure at the level of the 30-nm fiber, and 3) probe the relationship between primary sequence and functionality of macromolecules (RNA and protein). All of these research endeavors lie at the intersection of physics, engineering, and biology, and require the analysis of large, novel data sets.