Leslie (M.S. student) and Cally (M.S. student) each had their research accepted for presentation at ABRCMS (Annual Biomedical Research Conference for Minoritized Scientists) in Pittsburgh, PA.
Perla (PhD student) had her research accepted for presentation at SACNAS’ (Society for the Advancement of Chicanos/Hispanics and Native Americans in Science) annual NDiSTEM conference in Phoenix, AZ. Perla is also the recipient of the Travel Scholarship for the 2024 NDiSTEM Conference.
RNA secondary and tertiary structure is critically involved in ribozyme and ribosomal rRNA function, as well as viral and cellular regulation. Traditional experimental methods for RNA structure determination such as X-ray crystallography or chemical mapping are incisive; however, these approaches suffer from low-throughput and low-dimensionality, respectively. Computational approaches, leveraging evolutionary signals from correlated positions’ mutations, provide an alternative means to infer RNA structures. However, these methods require assembly, and face challenges due to statistical biases inherent in multiple sequence alignment (MSA). Furthermore, these methods cannot make use of the full spectrum of natural variations seen for a given RNA element.
Read it here:
https://www.biorxiv.org/content/10.1101/2024.10.03.616574v1
The SPLASH2 paper from the Salzman Lab was published online in Nature Biotechnology:
Title: Scalable and unsupervised discovery from raw sequencing reads using SPLASH2
Link: https://www.nature.com/articles/s41587-024-02381-2
·Authors:
Congrats, team!!
| Gowri Nayar, DBDS Ph.D. student advised by Prof. Russ Altman, has been awarded the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (F31) by the National Library of Medicine (NLM).
Congratulations, Gowri! |