Research News

Teri Klein, Russ Altman and Tiffany Murray book, Pacific Symposium on Computing 2025 just published

Teri Klein, Russ Altman and Tiffany Murray book, Pacific Symposium on Computing 2025 just published

BIOCOMPUTING 2025 – PROCEEDINGS OF THE PACIFIC SYMPOSIUM (https://doi.org/10.1142/14153), edited by Teri E. Klein, Russ Altman and Tiffany Murray has recently been published.

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Gevaert group published in Nature Machine Intelligence: Towards a more inductive world for drug repurposing approaches

Gevaert group published in Nature Machine Intelligence: Towards a more inductive world for drug repurposing approaches

Nature Machine Intelligence: https://www.nature.com/articles/s42256-025-00987-y#Sec2 In collaboration with Dr. Mikel Hernaez at CIMA, the Gevaert lab has benchmarked inductive and transductive methods for drug target interaction discovery.
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James Zou wins Overton Prize

James Zou wins Overton Prize

DBDS’ James Zou awarded Overton Prize

Awarded by ISCB, the prize recognizes the research, education, and service accomplishments of early to mid-career scientists who are emerging leaders in computational biology.

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Christina Curtis in the Stanford Report: Studying DNA variations in breast cancer tumors could improve treatment and recurrence screening

Christina Curtis in the Stanford Report: Studying DNA variations in breast cancer tumors could improve treatment and recurrence screening

“My lab has had a long-standing interest in understanding how aggressive breast tumors arise, why they are resistant to therapy,

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Manny Rivas and Larissa Lauer in BioRx: Unified meta regression models for rare variant association studies

Manny Rivas and Larissa Lauer in BioRx: Unified meta regression models for rare variant association studies

Rare variant association studies (RVAS) of complex traits have emerged as a powerful approach to advance drug discovery and diagnostics.

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James Zou: “The rise of agentic AI teammates in medicine,” The Lancet, 2/8 issue

James Zou: “The rise of agentic AI teammates in medicine,” The Lancet, 2/8 issue

“Medicine is in the dawn of a fundamental shift from using artificial intelligence (AI) as tools to deploying AI as agents.

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Collaboration and Careers Forum Overview 2025

Collaboration and Careers Forum Overview 2025

“This is a new era for us,” Chair of the Department of Biomedical Data Science Sylvia Plevritis began, opening the third annual Collaboration &

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Purvesh Khatri and Tim Sweeney get FDA clearance for TriVerity

Purvesh Khatri and Tim Sweeney get FDA clearance for TriVerity

For the past decade, Purvesh Khatri and team  have been working on developing blood-based signatures for presence, type, and severity of infection.
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Zou Group has new precision oncology paper published in Nature Communications

Zou Group has new precision oncology paper published in Nature Communications

The Zou Group is excited to announce that a new precision oncology paper published in Nature Communications https://www.nature.com/articles/s41467-024-55251-5.

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Gevaert Lab has developed SEQUOIA

Gevaert Lab has developed SEQUOIA

The Gevaert Lab has developed SEQUOIA, a transformer model that predicts cancer transcriptomic profiles from whole slide images, enabling cost-effective genetic insights from H&E images.

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Led by Eric Sun, the Zou Group’s new paper is published in Nature

Led by Eric Sun, the Zou Group’s new paper is published in Nature

The Zou Group is very excited to have a new paper on spatial single-cell aging clocks published in Nature,  led by DBDS PhD student Eric Sun.

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Zou Group paper published in Nature Biomedical Engineering

Zou Group paper published in Nature Biomedical Engineering

“Simple and effective embedding model for single-cell biology built from ChatGPT” from the Zou Group has been published in Nature Biomedical Engineering.

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Roxana Daneshjou’s redteaming work is explored in the Washington Post story

Roxana Daneshjou’s redteaming work is explored in the Washington Post story

Doctors are using AI. Will it make healtchcare better or break it? 

Millions are already being treated by doctors using artificial intelligence to take notes and draft emails to patients.

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The Zou group has 11 papers published in Neurips 2024

The Zou group has 11 papers published in Neurips 2024

The Zou group is excited to share that they have 11 papers published in Neurips 2024, one of the main AI conferences.

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Careers and Collaboration Event: January 16th, 2025 — register now!

Careers and Collaboration Event: January 16th, 2025 — register now!

This event aims to connect leaders from various sectors with our faculty, students, and staff to discuss advancements in AI,

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Tina Hernandz-Boussard and team put MLOps framework through an equity lens: NLM PubMed Central

Tina Hernandz-Boussard and team put MLOps framework through an equity lens: NLM PubMed Central

Machine learning operations (MLOps), a discipline concerned with the production, monitoring and maintenance of artificial intelligence (AI) and machine learning (ML) models at scale,

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James Zou: ChatGPT is changing peer review….

James Zou: ChatGPT is changing peer review….

James Zou: ChatGPT is changing peer review — how can we use it responsibly? Up to 17% of the peer reviews are written by artificial intelligence at major computer-science publication venues.
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DBDS Awarded $8.9 Million From ARPA-H to Support AI Tumor Board Research

DBDS Awarded $8.9 Million From ARPA-H to Support AI Tumor Board Research

An award of up to $8.9 million from The Advanced Research Projects Agency for Health (ARPA-H) to the Stanford Department of Biomedical Data Science (DBDS) will fund Stanford researchers in the development of AI-augmented support tools for cancer tumor boards.

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Quantitative Sciences Unit and Stanford Data Science are hosting an AI-themed symposium

Quantitative Sciences Unit and Stanford Data Science are hosting an AI-themed symposium

The focus: integrating AI into the data scientist’s workflow, discuss challenges and solutions, implications for the next generation, where we would address how the field is/should be evolving,

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Dr. Aaron Newman  promoted to Associate Professor

Dr. Aaron Newman promoted to Associate Professor

We are delighted to announce that Dr. Aaron Newman has been promoted to the role of Associate Professor of Biomedical Data Science.

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The Data Driver: How Tina Hernandez-Boussard is Shaping Inclusive Health Care

The Data Driver: How Tina Hernandez-Boussard is Shaping Inclusive Health Care

The Data Driver: How Tina Hernandez-Boussard is Shaping Inclusive Health Care (SOM Annual Report): “Data was my ticket to a different world,” she recalls.
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The Shah Group has new systematic review in JAMA Network: Testing and Evaluation of Health Care Applications of Large Language Models (and it’s free!)

The Shah Group has new systematic review in JAMA Network: Testing and Evaluation of Health Care Applications of Large Language Models (and it’s free!)

The Shah Group has a new  systematic review — https://jamanetwork.com/journals/jama/fullarticle/2825147 — in JAMA on Testing and Evaluation of Health Care Applications of Large Language Models,

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Wing Wong, co-author: Complex genomic variants are related to psychiatric diseases, study finds

Wing Wong, co-author: Complex genomic variants are related to psychiatric diseases, study finds

Stanford Medicine researchers, after creating an AI-based algorithm to find complex structural variants in the human genome, learned those variants likely contribute to psychiatric disease.
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Leslie Espinoza, Cally Lin, and Perla Molina are the DBDS Student JEDI Committee’s conference scholars and recruitment scouts for 2024! 

Leslie Espinoza, Cally Lin, and Perla Molina are the DBDS Student JEDI Committee’s conference scholars and recruitment scouts for 2024! 

Leslie (M.S. student) and Cally (M.S. student) each had their research accepted for presentation at ABRCMS (Annual Biomedical Research Conference for Minoritized Scientists) in Pittsburgh,

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Julie Wang and Arjun Rustagi have collaborated to generate a new method for detecting elements in viruses under selection

Julie Wang and Arjun Rustagi have collaborated to generate a new method for detecting elements in viruses under selection

RNA secondary and tertiary structure is critically involved in ribozyme and ribosomal rRNA function, as well as viral and cellular regulation.

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The SPLASH2 paper from the Salzman Lab was published online in Nature Biotechnology:

The SPLASH2 paper from the Salzman Lab was published online in Nature Biotechnology:

The SPLASH2 paper from the Salzman Lab was published online in Nature Biotechnology:

Title: Scalable and unsupervised discovery from raw sequencing reads using SPLASH2
Link: https://www.nature.com/articles/s41587-024-02381-2

·Authors:

  • Marek Kokot*,
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Gowri Nayar awarded NRSA F31 fellowship

Gowri Nayar awarded NRSA F31 fellowship

Gowri Nayar, DBDS Ph.D. student advised by Prof. Russ Altman, has been awarded the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (F31) by the National Library of Medicine (NLM).
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SoM Dean Minor joins Washington Post to discuss how AI can transform the patient journey in health care

SoM Dean Minor joins Washington Post to discuss how AI can transform the patient journey in health care

SoM Dean Minor discusses AI Tumor Boards; AI in scanning pathology slides, AI biases and how AI can impact patient outcomes and treatment.

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Monday Student Talks Have Returned: Erin Craig and Matt Aguirre

Monday Student Talks Have Returned: Erin Craig and Matt Aguirre

Erin Craig, 6th Year PhD Student
(12:15pm-12:45pm)
Title: MMIL: A novel algorithm for disease associated cell type discovery
Abstract: Single-cell datasets often lack individual cell labels,

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Nigam Shah: Researchers create guide for fair and equitable AI in health care

Nigam Shah: Researchers create guide for fair and equitable AI in health care

It’s time to put that technology to work widely — in ways that prioritize conscientious protocols designed to prevent bias in data gathering and use in patient care,

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Tina Hernandez-Boussard: Why ending ‘structural racism’ in health care now is crucial

Tina Hernandez-Boussard: Why ending ‘structural racism’ in health care now is crucial

As artificial intelligence changes the way medicine is practiced, humans become more beholden to algorithms — making it crucial to get those machine-human collaborations correct at the outset.

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EchoNet, developed by the Zou Lab, is approved by FDA

EchoNet, developed by the Zou Lab, is approved by FDA

EchoNet, developed by the Zou Lab, is advanced image post-processing analysis software designed to aid diagnostic review, analysis, and reporting of echocardiographic DICOM images for cardiac function,

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Dr. Tanveer Syeda-Mahmood is a co-author for survey article published in the International Journal of Computer Vision

Dr. Tanveer Syeda-Mahmood is a co-author for survey article published in the International Journal of Computer Vision

A survey article on multimodal models for clinical biomedicine was published in the International Journal of Computer Vision for which DBDS adjunct faculty Dr.

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DBDS’ Nigam Shah on AI Grand Rounds podcast

DBDS’ Nigam Shah on AI Grand Rounds podcast

In this episode of the AI Grand Rounds podcast, Dr. Nigam Shah, a distinguished Professor of Medicine at Stanford University and inaugural Chief Data Scientist for Stanford Health Care,

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Sohaib Hassan, Elana Simon and Selina Junyi Pi awarded the NSF Graduate Research Fellowship Program

Sohaib Hassan, Elana Simon and Selina Junyi Pi awarded the NSF Graduate Research Fellowship Program

Congratulations to Sohaib Hassan, Elana Simon and Selina Junyi Pi who were all awarded the NSF Graduate Research Fellowship Program (GRFP).

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The Stanford Center for Cancer Systems Biology Seminar Series: Dr. Sean Bendall, “Multi-generational decisions in single cell biology” 4/19

The Stanford Center for Cancer Systems Biology Seminar Series: Dr. Sean Bendall, “Multi-generational decisions in single cell biology” 4/19

Please join us at the next monthly CCSB Seminar, Friday, April 19, from 11 AM to 12 PM.

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Olivier Gevaert: “Generation of synthetic whole-slide image tiles of tumours from RNA-sequencing data via cascaded diffusion models” published in Nature Biomedical Engineering

Olivier Gevaert: “Generation of synthetic whole-slide image tiles of tumours from RNA-sequencing data via cascaded diffusion models” published in Nature Biomedical Engineering

Olivier Gevaert and team have developed a biomedical model inspired by DALL-E, we use RNA expression profiles to generate synthetic digital pathology images across several cancer tissues.
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AI’s future in medicine the focus of Stanford Med Live event

AI’s future in medicine the focus of Stanford Med Live event

Leaders of Stanford Medicine discuss artificial intelligence in health and medicine; its usefulness in research, education and patient care; and how to responsibly integrate the technology.

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Tanveer Syeda-Mahmood’s research featured in cover story for Nature Medicine Intelligence

Tanveer Syeda-Mahmood’s research featured in cover story for Nature Medicine Intelligence

Understanding the genetic factors that underlie the normal variation in cardiac anatomy is of great interest. In this study, Rodrigo Bonazzola et al.

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The ClinGen Pharmacogenomics Working Group: Exploring new directions and the evolution of PGx and genomic medicine

The ClinGen Pharmacogenomics Working Group: Exploring new directions and the evolution of PGx and genomic medicine

The ClinGen Pharmacogenomics Working Group: Developing frameworks for evaluating pharmacogenomic gene validity and actionability
Read it here: https://www.sciencedirect.com/science/article/pii/S294977442400222X

Generating a framework for curating mechanism of disease in monogenic conditions: A consensus effort of the Gene Curation Coalition*
Read it here: https://www.gimopen.org/article/S2949-7744(24)00622-8/fulltext

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Nigam Shah on Clinical Changemakers podcast

Nigam Shah on Clinical Changemakers podcast

Professor Nigam Shah shares his early experiences with AI, called ‘application of reasoning’, how this has evolved, and how AI and web applications like ChatGPT have changed the landscape of how AI is being used. 

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DBDS PhD student Yusuf Roohani’s research featured in the New York Times

DBDS PhD student Yusuf Roohani’s research featured in the New York Times

DBDS PhD student Yusuf Roohani’s work on universal cell embeddings was featured in a New York Times article: “

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Nigam Shah cited in two STAT articles

Nigam Shah cited in two STAT articles

Hospitals struggle to validate AI-generated clinical summaries
Click here to read

AI health care companies say they’ll keep humans in the loop.

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$5 Million Warren Alpert Foundation Grant To Fund 15 Department of Biomedical Data Science Computational Biology/AI Scholars

$5 Million Warren Alpert Foundation Grant To Fund 15 Department of Biomedical Data Science Computational Biology/AI Scholars

A new $5 million grant from the Warren Alpert Foundation was recently awarded to the Department of Biomedical Data Science (DBDS) at the Stanford School of Medicine.

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Akshay Chaudhari’s group publishes new paper in Nature Medicine on adapting large language models for clinical text summarization tasks

Akshay Chaudhari’s group publishes new paper in Nature Medicine on adapting large language models for clinical text summarization tasks

Akshay Chaudhari’s group publishes new paper in Nature Medicine on adapting open-source and closed-source large language models for clinical text summarization tasks.

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Plevritis and Shah panelists for State of AI in Health and Medicine, 3/18

Plevritis and Shah panelists for State of AI in Health and Medicine, 3/18

StanfordMed LIVE: The State of AI in Health and Medicine

Join StanfordMed LIVE for this special panel discussion on the state of AI in health and medicine on March 18,

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DBDS’ Roxana Daneshjou was selected as 2024 recipient of the American Academy of Dermatology Young Investigator Award

DBDS’ Roxana Daneshjou was selected as 2024 recipient of the American Academy of Dermatology Young Investigator Award

DBDS’ Roxana Daneshjou was selected as 2024 recipient of the American Academy of Dermatology Young Investigator Award for her significant research advances in the science and practice of dermatology.

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James Zou team: New paper recently published in the Harvard Data Science Review

James Zou team: New paper recently published in the Harvard Data Science Review

James Zou team: New paper recently published in the Harvard Data Science Review discussing how data science can benefit from large language models (LLMs) https://hdsr.mitpress.mit.edu/pub/pqiufdew/release/2?readingCollection=3a653084.

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DBDS’ Nigam Shah: Healthcare Leaders and UK Government Discuss Safe Deployment of AI

DBDS’ Nigam Shah: Healthcare Leaders and UK Government Discuss Safe Deployment of AI

DBDS’ Nigam Shah: Healthcare Leaders and UK Government Discuss Safe Deployment of AI Healthcare leaders are currently engaged in vigorous discussions about the potential risks and responsibilities that come with the deployment of artificial intelligence (AI) in the sector.
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Tina Hernandez-Boussard’s paper on bias risks cited by White House AI Fact Sheet

Tina Hernandez-Boussard’s paper on bias risks cited by White House AI Fact Sheet

A recently published paper, “Guiding Principles to Address the Impact of Algorithm Bias on Racial and Ethnic Disparities in Health and Health Care,” of which Tina Hernandez-Boussard,

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Nigam Shah and partners roll out beta version of Stanford medicine SHC and SoM Secure GPT

Nigam Shah and partners roll out beta version of Stanford medicine SHC and SoM Secure GPT

Dear Stanford School of Medicine Community,

Stanford Medicine is committed to being digitally driven, adopting cutting-edge technologies that advance our missions of research,

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New paper from Julia Salzman in BioRxiv

New paper from Julia Salzman in BioRxiv

New paper from Julia Salzman in BioRxiv: Ultra-efficient, unified discovery from microbial sequencing with SPLASH and precise statistical assembly Bacteria comprise >
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Nima Aghaeepour’s study of preterm birth risks featured in Stanford Medicine

Nima Aghaeepour’s study of preterm birth risks featured in Stanford Medicine

Wearable device data reveals that reduced sleep and activity in pregnancy is linked to premature birth risk Data from wearables show that deviations from normal sleep and activity in pregnancy are connected to a risk for premature delivery,
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James Zou featured in WSJ on ChatGPT and medicine

James Zou featured in WSJ on ChatGPT and medicine

Should You Use ChatGPT for Medical Advice? Yes, patients and doctors can use chatbots for certain types of questions, experts say.
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Metastatic breast cancer treatments have aided decline in deaths, Stanford Medicine-led study finds (Plevritis Lab)

Metastatic breast cancer treatments have aided decline in deaths, Stanford Medicine-led study finds (Plevritis Lab)

Treatment of metastatic disease is responsible for nearly one-third of the decrease in annual deaths from breast cancer from 1975 to 2019,

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Julia Salzman’s new paper on SPLASH on Cell

Julia Salzman’s new paper on SPLASH on Cell

Julia Salzman’s new paper on Cell today:

Today’s genomics workflows typically require alignment to a reference sequence, which limits discovery.
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DBDS faculty featured prominently in cover story of latest SOM Magazine: “Medicine’s AI Boom: The Stanford Impact”

DBDS faculty featured prominently in cover story of latest SOM Magazine: “Medicine’s AI Boom: The Stanford Impact”

Eleven of DBDS’ faculty and associated faculty were featured in the latest issue of Stanford Medicine Magazine. “Medicine’s AI Boom: The Stanford Impact”
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Min Woo Sun and Robert Tibshirani publish “Public health factors help explain cross country heterogeneity in excess death during the COVID19 pandemic” in Nature Scientific Reports

Min Woo Sun and Robert Tibshirani publish “Public health factors help explain cross country heterogeneity in excess death during the COVID19 pandemic” in Nature Scientific Reports

Abstract

The COVID-19 pandemic has taken a devastating toll around the world. Since January 2020, the World Health Organization estimates 14.9 million excess deaths have occurred globally.

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Gina Bouchard: “The colocatome as a spatial -omic reveals shared microenvironment features between tumour-stroma assembloids and lung cancer specimens” published in BioRxiv

Gina Bouchard: Computational frameworks to quantify and compare microenvironment spatial features of in vitro patient-derived models and clinical specimens are needed.

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Gevaert team: Glioblastoma research study establishes a connection between spatial cellular architecture and clinical outcomes

Gevaert team: Glioblastoma research study establishes a connection between spatial cellular architecture and clinical outcomes

Exciting work in glioblastoma research spearheaded by postdoc Yuan-Ning Zheng. The Gevaert team has developed a deep learning model to predict transcriptional subtypes of glioblastoma cells from spatial transcriptomics data and histology images.

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